货号：AB9290

品牌：Merck Millipore

规格：

目录价：￥3767.00

市场价格：￥3201.95

会员价格：￥3013.60

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Contactin-1 Antibody | AB9290 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Contactin-1. View All» Immunogen: Synthetic peptide from rat Contactin-1. View All» Species Reactivity: Rat View All» Application Notes: Western blot: 1:1,000 on rat brain lysate. Reacts with the ~135 kDa Contactin-1 protein. Optimal working dilutions must be determined by the end user. View All» Presentation: Rabbit serum. Liquid. View All» Storage Conditions: Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles. View All» UniProt Number: Q12860 View All» Entrez Gene Number:

• NM_001843.2

• NM_175038.1
  View All» Gene Symbol:
  • CNTN1

  • GP135

  • F3
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» Entrez Gene Summary: The protein encoded by this gene is a member of the immunoglobulin superfamily. It is a glycosylphosphatidylinositol (GPI)-anchored neuronal membrane protein that functions as a cell adhesion molecule. It may play a role in the formation of axon connections in the developing nervous system. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. View All» UniProt Summary: FUNCTION: SwissProt: Q12860 # Contactins mediate cell surface interactions during nervous system development. Involved in the formation of paranodal axo-glial junctions in myelinated peripheral nerves and in the signaling between axons and myelinating glial cells via its association with CNTNAP1. Participates in oligodendrocytes generation by acting as a ligand of NOTCH1. Its association with NOTCH1 promotes NOTCH1 activation through the released notch intracellular domain (NICD) and subsequent translocation to the nucleus. Interaction with TNR induces a repulsion of neurons and an inhibition of neurite outgrowth (By similarity).SIZE: 1018 amino acids; 113320 Da SUBUNIT: Interacts with CNTNAP1 in cis form. Binds to the carbonic-anhydrase like domain of protein-tyrosine phosphatase zeta. Interacts with NOTCH1 and TNR (By similarity).SUBCELLULAR LOCATION: Isoform 1: Cell membrane; Lipid-anchor, GPI- anchor; Extracellular side. & Isoform 2: Cell membrane; Lipid-anchor, GPI- anchor; Extracellular side.SIMILARITY: SwissProt: Q12860 ## Belongs to the immunoglobulin superfamily. Contactin family. & Contains 4 fibronectin type-III domains. & Contains 6 Ig-like C2-type (immunoglobulin-like) domains. View All» Brand Family: Chemicon View All» Product Name: Anti-Contactin-1 Antibody | AB9290 View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 µL View All» Target / Localization: Cell junctions, Cytoplasmic View All» Format: Serum View All» Host: Rabbit View All»
    © 金山科研平台是专业的授权总代理区域代理经销平台。
    © 如需询价，请加客服QQ：1749072012 、客服微信：jinshanbio，或发送邮件到1749072012@qq.com
    © 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务，数据资源基于CC协议。
    © 本文地址：http://16ao.com/thread-158496.htm
    © Merck Millipore代理AB9290 Rb X Contactin-1，产品报价联系微信jinshanbio