货号：AB3475

品牌：Merck Millipore

规格：EA

目录价：询价

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-RNA Polymerase II (DNA directed) polypeptide C View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: POLR2C (DNA directed RNA polymerase II polypeptide C) View All» Immunogen: Human POLR2C, full length protein. View All» Species Reactivity: Human View All» Application Notes: Western blot: 1:500-1:2,000 (colormetric) It is expected that the antibody will also work for immunocytochemistry and immunohistochemistry. Specific reactivity has not been confirmed. Optimal working dilutions must be determined by the end user. View All» Presentation: Affinity purified immunoglobulin. Liquid in PBS. View All» Storage Conditions: Maintain at -20°C in undiluted aliquots up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles. View All» UniProt Number: P19387 View All» Entrez Gene Number: NM_032940.2 View All» Gene Symbol:

• POLR2C

• RPB31

• hsRPB3

• RPB3

• RPB33

• ORFNames=A-152E5.7

• hRPB33
  View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» Entrez Gene Summary: This gene encodes the third largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a cysteine rich region and exists as a heterodimer with another polymerase subunit, POLR2J. These two subunits form a core subassembly unit of the polymerase. A pseudogene has been identified on chromosome 21. View All» UniProt Summary: FUNCTION: SwissProt: P19387 # DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB3 is part of the core element with the central large cleft and the clamp element that moves to open and close the cleft (By similarity).SIZE: 275 amino acids; 31441 Da SUBUNIT: Component of the RNA polymerase II (Pol II) complex consisting of 12 subunits. RPB11/POLR2J and RPB3/POLR2C subunits interact with each other.SUBCELLULAR LOCATION: Nucleus.SIMILARITY: SwissProt: P19387 ## Belongs to the archaeal rpoD/eukaryotic RPB3 RNA polymerase subunit family. View All» Brand Family: Chemicon View All» Product Name: Anti-RNA Polymerase II (DNA directed) polypeptide C View All» Concentration: 1 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 µg View All» Format: Affinity Purified View All» Host: Chicken View All»
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