货号:14-688
品牌:Merck Millipore
规格:10Ug
目录价:¥6586.00
市场价格:¥5598.10
会员价格:¥5268.80
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Description:
PKG1α, active
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Trade Name:
Upstate (Millipore)
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Qty/Pk:
10 µg
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Product Overview:
N-terminal 6His-tagged, recombinant, full length PKG1α.
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Key Applications:
Kinase Assay
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Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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UniProt Summary:
SIZE: 686 amino acids; 77804 Da SUBUNIT: Antiparallel homodimer. Part of cGMP kinase signaling complex at least composed of ACTA2/alpha-actin, CNN1/calponin H1, PLN/phospholamban, PRKG1 and ITPR1 (By similarity). Interacts with MRVI1.DOMAIN: SwissProt: P14619 SIMILARITY: SwissProt: P14619 ## Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cGMP subfamily. & Contains 1 AGC-kinase C-terminal domain. & Contains 2 cyclic nucleotide-binding domains. & Contains 1 protein kinase domain. | Q13976 ## Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cGMP subfamily. & Contains 1 AGC-kinase C-terminal domain. & Contains 2 cyclic nucleotide-binding domains. & Contains 1 protein kinase domain. MISCELLANEOUS: Exhibit a substrate specificity similar but not identical to that of CAK.
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Species:
Human
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Molecular Weight:
80kDa
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Brand Family:
Upstate
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Source:
PKG1α, expressed by baculovirus in Sf21 cells.
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Protein Target:
PKG1α
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Storage Conditions:
6 months at -70°C from date of shipment
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Target Sub-Family:
AGC
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Gene Symbol:
-
PRKG1
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cGKI-beta
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FLJ36117
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PGK
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PRKGR1A
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cGKI-alpha
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cGKI
-
MGC71944
-
OTTHUMP00000061216
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CGKI
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PRKG1B
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cGKI-BETA
-
PRKGR1B
-
DKFZp686K042
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Product Name:
PKG1α, active
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Quality Assurance:
routinely evaluated by phosphorylation of PAKtide (RRRLSFAEPG).
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UniProt Number:
P14619
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Specific Activity:
For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
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Entrez Gene Number:
-
NM_001098512.1
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NM_006258.2
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Purification Method:
Ni2+/NTA-agarose
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