R&D Systems代理AF4738 Human Talin2 Affinity Purified Polyclonal Ab (100 UG)

2025-07-23

货号:AF4738

品牌:R&D Systems

规格:100ug

目录价:¥5040.00

市场价格:¥4032.00

会员价格:¥4032.00

  • 到货时间:3~4周

    金山科研平台,产品价格货期咨询微信:jinshanbio Molecule Information: Talin2 Aliases: ILWEQ; TLN2 Entrez Gene IDs: 83660 (Human); 70549 (Mouse); 315776 (Rat) Background: Talin2 Talin2 (talus; Latin for ankle, the shape of a focal adhesion plaque complex) is a 240 kDa cytoplasmic focal adhesion molecule. It likely forms dimers that link integrins to the actin cytoskeleton. Human Talin2 is 2542 amino acids (aa) in length. It contains one globular N-terminal FERM domain that binds integrin cytodomains (aa 88-406), followed by an Ala-rich region (aa 861-1193) and a C-terminal actin-binding domain (aa 2321-2530). Human Talin2 has three potential variants. Two show alternate start sites at Met19 and Met1153, while a third has an alternate start site at Met1608 accompanied by a deletion of aa 1748-1790. Over aa's 977-1183, human Talin2 shares 99% and 97% aa identity with canine and mouse Talin2, respectively.

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