货号:14-632
品牌:Merck Millipore
规格:
目录价:¥4497.00
市场价格:¥3822.45
会员价格:¥3597.60
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Description:
TSSK2, active
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Trade Name:
Upstate (Millipore)
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Qty/Pk:
10 µg
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Product Overview:
N-terminal His6-tagged, recombinant, full length, human TSSK2, expressed by baculovirus in Sf21 insect cells
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Key Applications:
Kinase Assay
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Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Entrez Gene Summary:
TSSK2 belongs to a family of serine/threonine kinases highly expressed in testis (Hao et al., 2004 [PubMed 15044604]).[supplied by OMIM]
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UniProt Summary:
FUNCTION: SwissProt: Q96PF2 # Involved in the late stages of spermatogenesis, during the reconstruction of the cytoplasm (By similarity).COFACTOR: Magnesium (By similarity).SIZE: 358 amino acids; 40939 Da SUBUNIT: Binds to STK22A (By similarity).SUBCELLULAR LOCATION: Cytoplasm (By similarity).TISSUE SPECIFICITY: Testis.PTM: Autophosphorylated (By similarity).DISEASE: SwissProt: Q96PF2 # May play a part in the etiology of the velocardiofacial/DiGeorge syndrome (VCFS/DGS), a developmental disorder characterized by structural and functional palate anomalies, conotruncal cardiac malformations, immunodeficiency, hypocalcemia, and typical facial anomalies. Most cases result from a deletion of chromosome 22q11.2 (the DiGeorge syndrome chromosome region, or DGCR).SIMILARITY: SwissProt: Q96PF2 ## Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. & Contains 1 protein kinase domain.
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Species:
Human
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Molecular Weight:
44.8kDa
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Brand Family:
Upstate
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Source:
full length, human TSSK2
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Protein Target:
TSSK2
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Storage Conditions:
6 months at -70°C
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Target Sub-Family:
CAMK
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Promotional Text:
This enzyme is part of KinaseProfiler™, a custom inhibitor selectivity discovery service.
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Gene Symbol:
-
TSSK2
-
FLJ38613
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DGSG
-
SPOGA2
-
TSK-2
-
STK22B
-
DGS-G
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Product Name:
TSSK2, active
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Quality Assurance:
routinely evaluated by phosphorylation of CHKtide
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UniProt Number:
Q96PF2
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Specific Activity:
For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
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Entrez Gene Number:
NM_053006.3
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Purification Method:
Ni2+/NTA-agarose
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