金山科研平台，产品价格货期咨询微信：jinshanbio Source:Chinese Hamster Ovary cell line, CHO-derived Accession #:EDL34457 N-terminal Sequence Analysis:Leu18 Structure:Disulfide-linked homodimer Purity:>90%, by SDS-PAGE under reducing conditions and visualized by silver stain. Predicted Molecular Mass:43.6 kDa (monomer) SDS-PAGE:55-60 kDa, reducing conditions Activity:Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated human T cells.The ED₅₀ for this effect is typically 0.75-3.5 µg/mL.Optimal dilutions should be determined by each laboratory for each application. Formulation:Lyophilized from a 0.2 µm filtered solution in PBS.See Certificate of Analysis for details. Molecule Information: CD300e/LMIR6 Aliases: CD300e; CD300LE; CLM2; IREM-2; LMIR6 Entrez Gene IDs: 342510 (Human); 217306 (Mouse) Background: CD300/LMIRs The CD300, alternately designated the LMIR family, contains six to eight type I membrane proteins expressed mainly on cells of the myeloid lineage. Each has a single extracellular V-type Ig-like domain. Some have cytoplasmic ITIM motifs that result in the delivery of an inhibitory signal; others can interact with ITAM motifs and function as activating receptors. Human CD300 proteins have also been designated IREM (immune receptor expressed by myeloid cells) or CMRF-35 for the original identifying antibody; mouse CD300 proteins have alternate naming as CLM (CMRF-35-like molecules).