R&D Systems代理7044-CB-050 Recombinant Human Cerebellin-2 Protein, CF (50 UG)

2025-07-24

货号:7044-CB-050

品牌:R&D Systems

规格:50ug

目录价:¥4490.00

市场价格:¥3592.00

会员价格:¥3592.00

  • 到货时间:3~4周

    金山科研平台,产品价格货期咨询微信:jinshanbio Source:Chinese Hamster Ovary cell line, CHO-derived, Arg50-Leu224, with an N-terminal HA (YPYDVPDYA) tag Accession #:Q8IUK8 N-terminal Sequence Analysis:Tyr Purity:>85%, by SDS-PAGE under reducing conditions and visualized by silver stain. Endotoxin Level: Predicted Molecular Mass:20 kDa SDS-PAGE:25-35 kDa, reducing conditions Activity:Measured by its binding ability in a functional ELISA.When Recombinant Human Cerebellin-2 is coated at 5 µg/mL,biotinylated recombinant rat NRXN-1 beta binds with an apparent KD<1.5 nM.Measured by its ability to enhance neurite outgrowth of E16-E18 rat embryonic cortical neurons.Recombinant Human Cerebellin-2, immobilizedat3-30 µg/mL, is able to significantly enhance neurite outgrowth. Formulation:Lyophilized from a 0.2 µm filtered solution in PBS.See Certificate of Analysis for details. Molecule Information: Cerebellin-2 Aliases: CBLN2 Entrez Gene IDs: 147381 (Human); 12405 (Mouse); 291388 (Rat) Background: Cerebellin-2

    View Cerebellin-2 IHC images. Cerebellin-2 (CBLN2) is an approximately 25 kDa glycoprotein in the Cerebellin family of C1q- and TNF-related proteins. It contains a potential membrane-associating segment but may also be secreted. It contains one C1q-like domain in its extracellular region. Cerebellin-2 expression is developmentally regulated in the cerebellum, neocortex, sensory neurons of the dorsal root ganglion and spinal cord, and adrenal cortex. It associates with Cerebellin-1 which is involved in the formation and maintenance of synapses in the cerebellum. Within the ectodomain (aa 50-224), Human Cerebellin-2 shares 99% aa sequence identity with mouse and rat Cerebellin-2.

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