金山科研平台，产品价格货期咨询微信：jinshanbio Source:Mouse myeloma cell line, NS0-derived, Met1-Phe141, with a C-terminal 6-His tag Accession #:P43407 N-terminal Sequence Analysis:Glu19 Purity:>95%, by SDS-PAGE under reducing conditions and visualized by silver stain. Predicted Molecular Mass:14.2 kDa SDS-PAGE:30-40 kDa, reducing conditions Activity:Measured by the ability of the immobilized protein to support the adhesion of the LCells mouse fibroblast cell line.When 5 x 10⁴ cells/well are added to Recombinant Mouse Syndecan-2 and Human Fibronectin (0.5 µg/mL, Catalog #1918-FN) coated plates, cell adhesion is enhanced in a dose dependent manner after 30 minutes at 37°C. The ED₅₀ for this effect is typically 1.5 - 6.0 µg/mL. Formulation:Lyophilized from a 0.2 µm filtered solution in PBS.See Certificate of Analysis for details. Molecule Information: Syndecan-2 Aliases: CD362; Fibroglycan; HSPG1; SDC2; SYND2 Entrez Gene IDs: 6383 (Human); 15529 (Mouse) Background: Syndecan Family Syndecans are type 1 transmembrane proteoglycans that constitute the major physiological form of heparan sulfate (HS) on the cell surface. The four vertebrate syndecans, Syndecan-1 through -4, have similar short cytoplasmic domains and extracellular portions that diverge, except for HS attachment sites. Structurally diverse side chains add considerably to the size of the core proteins and serve as binding sites for growth factors, cytokines, and extracellular matrix proteins. Syndecans are present as homodimers or multimers, and are often expressed in developmental and cell type-specific patterns. They have many biological roles including regulating cell growth, differentiation, and adhesion.