金山科研平台，产品价格货期咨询微信：jinshanbio Source:Chinese Hamster Ovary cell line, CHO-derived, Gln34-Thr1427, with a C-terminal 10-His tag Accession #:Q76LX8 N-terminal Sequence Analysis:Ala75 Purity:>90%, by SDS-PAGE under reducing conditions and visualized by Colloidal Coomassie® Blue stain at 5 µg per lane. Endotoxin Level: Predicted Molecular Mass:147 kDa SDS-PAGE:160-180 kDa, reducing conditions Activity:Measured by its ability to cleave Recombinant Human vWF‑A2 (Catalog# 2764-WF).Recombinant Human ADAMTS13 achieves >50% substrate cleavage, as measured under the described conditions. Formulation:Supplied as a 0.2 µm filtered solution in HEPES, NaCl, CaCl₂ and Brij-35.See Certificate of Analysis for details. Molecule Information: ADAMTS13 Long Name: A Disintegrin-like and Metalloproteinase Domain with Thrombospondin Motifs 13 Aliases: TTP; vWF-CP Entrez Gene IDs: 11093 (Human); 279028 (Mouse); 362091 (Rat) Background: ADAMTSs (ADAM metalloprotease with ThromboSpondin type 1 motif) Members of the ADAMTS family contain pro, catalytic, disintegrin-like, cysteine-rich, spacer and a variable number of TS type 1 motifs. In contrast to membrane-anchored ADAMs, ADAMTSs are secreted and are all active proteases. They are essential for aggrecan turnover and procollagen processing, regulation of which is important in many physiological and pathological processes such as angiogenesis and arthritis.