货号：07-613

品牌：Merck Millipore

规格：EA

目录价：￥4390.00

市场价格：￥3731.50

会员价格：￥3512.00

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Thioredoxin Reductase 1 (TrxR1) Antibody | 07-613 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Upstate (Millipore) View All» Specificity: thioredoxin reductase 1 View All» Molecular Weight: 58kDa View All» Immunogen: peptide corresponding to amino acids 137-150 (C-PHRIKATNNKGKEK) of human thioredoxin reductase 1 View All» Isotype: IgG View All» Species Reactivity:

• Human

• Rat
  View All» Quality Assurance: routinely evaluated by immunoblot in RIPA lysates from rat brain microsomal preparation View All» Purification Method: Immunoaffinity purified View All» Presentation: 0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30% View All» Storage Conditions: 1 year at -20°C View All» UniProt Number: Q16881 View All» Entrez Gene Number: NM_003330 View All» Gene Symbol:
  • TXNRD1

  • TXNR

  • oxidoreductase

  • TRXR1

  • Trxr1

  • MGC9145

  • TR

  • GRIM-12

  • TR1
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • Western Blotting

    • Immunocytochemistry
      View All» Entrez Gene Summary: This gene encodes a member of the family of pyridine nucleotide oxidoreductases. This protein reduces thioredoxins as well as other substrates, and plays a role in selenium metabolism and protection against oxidative stress. The functional enzyme is thought to be a homodimer which uses FAD as a cofactor. Each subunit contains a selenocysteine (Sec) residue which is required for catalytic activity. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenocysteine-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing results in several transcript variants encoding the same or different isoforms. View All» UniProt Summary: COFACTOR: Binds 1 FAD per subunit.SIZE: 499 amino acids; 54707 Da SUBUNIT: Homodimer.SUBCELLULAR LOCATION: Cytoplasm (By similarity).PTM: The N-terminus is blocked. & Contains a selenide-sulfide bond between Cys-497 and Sec-498. This bond is speculated to serve as redox active pair (By similarity).SIMILARITY: SwissProt: Q16881 ## Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.MISCELLANEOUS: The active site is a redox-active disulfide bond. View All» Brand Family: Upstate View All» Product Name: Anti-Thioredoxin Reductase 1 (TrxR1) Antibody | 07-613 View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 µg View All» Format: Affinity Purified View All» Host: Rabbit View All»
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