Merck Millipore代理06-1038 Anti-Unc84B/SUN2 Antibody;store at +2℃ to +8℃

2025-07-22

货号:06-1038

品牌:Merck Millipore

规格:100Ug

目录价:¥4530.00

市场价格:¥3850.50

会员价格:¥3624.00

金山科研平台,产品价格货期咨询微信:jinshanbio Description: Anti-Unc84B/SUN2 Antibody | 06-1038 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Specificity: This antibody recognizes Unc84B/SUN2 at the N-terminus. View All» Molecular Weight: ~80 kDa View All» Epitope: N-terminus View All» Immunogen: KLH-conjugated linear peptide corresponding to human Unc84B/SUN2 at and around the N-terminus. View All» Isotype: IgG View All» Background Information: UNC84B (Protein UNC-84 homolog B or SUN2), is a single-pass nuclear envelope transmembrane protein responsible for nuclear migrations that are essential for development. UNC-84B has a predicted transmembrane domain and a C-terminal region with similarity to the S. pombe spindle pole body protein Sad1. UNC-84B interacts with RAB5A and is widely expressed, and highly expressed in the heart, lungs and muscles. UNC-84 may function to facilitate a nuclear-centrosomal interaction required for nuclear migration and anchorage. View All» Species Reactivity:

  • Human

  • Canine

  • Horse

    View All» Species Reactivity Note: Proven to react with human. Predicted to react with dog and horse based on sequence homology. Mouse and rat (87%). View All» Application Notes: Immunoprecipitation Analysis: 10 µg from a previous lot immunoprecipitated Unc84B/SUN2 from 500 µg of U2OS cell lysate. View All» Control: U2OS cell lysate. View All» Quality Assurance: Evaluated by Western Blotting in U2OS cell lysate.Western Blot (SNAP ID) Analysis: 1:250 dilution of this antibody detected Unc84B/SUN2 on 10 µg of U2OS cell lysate. View All» Purification Method: Affinity Purfied View All» Presentation: Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: Q9UH99 View All» Entrez Gene Number: NP_056189 View All» Gene Symbol:
    • FRIGG

    • UNC84B

    • RAB5IP

    • Rab5IP

    • SUN2

      View All» Alternate Names:
      • Rab5-interacting protein

      • Sad1 unc-84 domain protein 2

      • Sad1/unc-84 protein-like 2

      • nuclear envelope protein

      • unc-84 homolog B

      • unc-84 homolog B (C. elegans)

        View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
        • Immunoprecipitation

        • Western Blotting

          View All» UniProt Summary: SUBUNIT STRUCTURE: Interacts with RAB5A. SUBCELLULAR LOCATION: Nucleus membrane; Single-pass membrane protein. Endosome membrane; Single-pass membrane protein Probable. TISSUE SPECIFICTY: Widely expressed. Highly expressed in heart, lung and muscle. Weakly expressed in fetal heart. Slightly overexpressed in some heart tissues form patients with congenital heart defects.DOMAIN: The Unc84 domain may play a role in the nuclear anchoring and/or migration.SEQUENCE SIMILARITIES: Contains 1 Unc84 (SUN) domain.Caution It is uncertain whether Met-1 or Met-50 is the initiator. View All» Product Name: Anti-Unc84B/SUN2 View All» Concentration: 0.5 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Affinity Purified View All» Host: Rabbit View All»

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