货号：MABF79

品牌：Merck Millipore

规格：EA

目录价：￥3144.00

市场价格：￥2672.40

会员价格：￥2515.20

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-CD83 Antibody, clone HB15-206 | MABF79 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Molecular Weight: ~23 kDa observed View All» Immunogen: Recombinant protein corresponding to human CD83. View All» Clone: HB15-206 View All» Isotype: IgG1κ View All» Background Information: CD83 is a cell surface marker that is predominantly expressed on mature human and mouse dendritic cells (DCs). In humans, CD83 is expressed by circulating and tissue DCs, including interdigitating reticulum cells within the spleen, lymphocytes, Langerhan’s cells within the epidermis, and DCs within the thymic medulla, but can also be found in a select number of other cells depending on their condition or state of maturation. In mice, CD83 is expressed on the cell surface of mature DC populations, purified thymic DCs, lymphocytes, and bone marrow-derived DCs, among other select types of cells in certain conditions and states. Generally, CD83 expression correlates with upregulation of HLA class II antigen expression, and serves as a selective marker for DC maturation and activation. Its expression is essential for the regulation of immune system development and maintenance. View All» Species Reactivity: Human View All» Species Reactivity Note: Demonstrated to react with Human. View All» Application Notes: Flow Cytometry Analysis: 1 µg/mL from a representative lot detected CD83 in BDCM cells. View All» Control: Human tonsil tissue lysate View All» Quality Assurance: Evaluated by Western Blot in human tonsil tissue lysate.Western Blot Analysis: 0.5 µg/mL detected CD83 in 10 µg of human tonsil tissue lysate. View All» Purification Method: Protein G purified View All» Presentation: Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: Q01151 View All» Entrez Gene Number: NP_001035370 View All» Gene Symbol: CD83 View All» Alternate Names:

• CD83 antigen

• CD83

• B-cell activation protein

• Cell surface protein HB15
  View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
  • Western Blotting

  • Flow Cytometry
    View All» UniProt Summary: FUNCTION: May play a significant role in antigen presentation or the cellular interactions that follow lymphocyte activation.SUBUNIT STRUCTURE: Monomer.SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein. View All» Product Name: Anti-CD83 Antibody, clone HB15-206 | MABF79 View All» Concentration: 0.5 mg/mL View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Purified View All» Host: Mouse View All»
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