货号：MABE137

品牌：Merck Millipore

规格：

目录价：￥3999.00

市场价格：￥3399.15

会员价格：￥3199.20

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-CHD1 Antibody, clone 2F11H5 | MABE137 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Specificity: This antibody recognizes the C-terminus of CHD1. View All» Molecular Weight: ~196 kDa observed View All» Epitope: C-terminus View All» Immunogen: KLH-conjugated linear peptide corresponding to the C-terminus of mouse CHD1. View All» Clone: 2F11H5 View All» Isotype: IgG2aκ View All» Background Information: Chromodomain-helicase-DNA-binding protein 1 (CHD1) is a multidomain chromatin-remodelling enzyme, which belongs to the SNF2/RAD54 helicase family. It contains an SWI/SNF-like helicase/ATPase domain, a DNA-binding domain, and two chromodomains. CHD1 is multifunctional protein, which has an important role in gene regulation. It interacts with various modified histones, such as H3K4Me2 and H3K4Me3, and maintains the open chromatin structure required for transcription. It also interacts with, or plays a role in the assembly of, several transcription-related complexes, including the histone acetylation complex SAGA, and the FACT and PAF complexes. Previous studies have suggested that CHD1 maintains the pluripotent state of embryonic stem cells, and is required for the reprogramming of somatic cells to the pluripotent state. CHD1 may play a role in the development of prostate cancer. View All» Species Reactivity: Mouse View All» Application Notes: Immunocytochemistry Analysis: A representative lot was used by an independent laboratory in NIH/3T3 cells. (Yoshimura, S., et al. (2010). Hybridoma. 29(3):DOI: 10.1089=hyb.2009.0106.)Immunohistochemistry Analysis: A representative lot was used by an independent laboratory in E12.5 mouse heart tissue. (Yoshimura, S., et al. (2010). Hybridoma. 29(3):DOI: 10.1089=hyb.2009.0106.) View All» Control: NIH/3T3 nuclear extract View All» Quality Assurance: Evaluated by Western Blot in NIH/3T3 nuclear extract.Western Blot Analysis: 2 µg/mL of this antibody detected CHD1 in 10 µg of NIH/3T3 nuclear extract. View All» Purification Method: Protein G purified View All» Presentation: Purified rat monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: P40201 View All» Entrez Gene Number: NP_031716 View All» Gene Symbol:

• Chd1

• Chd-1
  View All» Alternate Names:
  • Chromodomain-helicase-DNA-binding protein 1

  • CHD-1

  • ATP-dependent helicase CHD1
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • Western Blotting

    • Immunocytochemistry

    • Immunohistochemistry
      View All» Product Name: Anti-CHD1, clone 2F11H5 View All» Concentration: 1 mg/mL View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Purified View All» Host: Rat View All»
      © 金山科研平台是专业的授权总代理区域代理经销平台。
      © 如需询价，请加客服QQ：1749072012 、客服微信：jinshanbio，或发送邮件到1749072012@qq.com
      © 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务，数据资源基于CC协议。
      © 本文地址：http://16ao.com/thread-132899.htm
      © Merck Millipore代理MABE137 Anti-CHD1, clone 2F11H5，产品报价联系微信jinshanbio