货号：MABD10

品牌：Merck Millipore

规格：

目录价：￥4146.00

市场价格：￥3524.10

会员价格：￥3316.80

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-DMP1, N-terminus Antibody, clone 9B6.3 | MABD10 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Specificity: This antibody recognizes the N-terminus of DMP1. View All» Molecular Weight: ~65 kDa observed. Uniprot describes a molecular weight at ~53 kDa. Uniprot describes that this protein is highly phosphorylated and highly glycosolated. View All» Epitope: N-terminus View All» Immunogen: N-terminus fragment of rat DMP1 isolated from long bone. View All» Clone: 9B6.3 View All» Isotype: IgG1κ View All» Background Information: Dentin matrix acidic phosphoprotein is an extracellular matrix protein and a member of the small integrin binding ligand N-linked glycoprotein family. This protein, which is critical for proper mineralization of bone and dentin, is present in diverse cells of bone and tooth tissues. The protein contains a large number of acidic domains, multiple phosphorylation sites, a functional arg-gly-asp cell attachment sequence, and a DNA binding domain. In undifferentiated osteoblasts it is primarily a nuclear protein that regulates the expression of osteoblast-specific genes. During osteoblast maturation the protein becomes phosphorylated and is exported to the extracellular matrix, where it orchestrates mineralized matrix formation. Mutations in the gene are known to cause autosomal recessive hypophosphatemia, a disease that manifests as rickets and osteomalacia. The gene structure is conserved in mammals. Two transcript variants encoding different isoforms have been described for this gene. View All» Species Reactivity: Rat View All» Species Reactivity Note: Demonstrated to react with Rat. View All» Control: Rat dentin tissue extract View All» Quality Assurance: Evaluated by Western Blot in rat dentin tissue extract.Western Blot Analysis: 1 µg/mL of this antibody detected DMP1 in 10 µg of rat dentin tissue extract. View All» Purification Method: Protein G purified View All» Presentation: Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: P98193 View All» Entrez Gene Number: NP_987089 View All» Gene Symbol: Dmp1 View All» Alternate Names:

• Dentin matrix acidic phosphoprotein 1

• DMP-1

• Dentin matrix protein 1

• AG1
  View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» Product Name: Anti-DMP1, N-terminus, clone 9B6.3 View All» Concentration: 1 mg/mL View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Purified View All» Host: Mouse View All»
  © 金山科研平台是专业的授权总代理区域代理经销平台。
  © 如需询价，请加客服QQ：1749072012 、客服微信：jinshanbio，或发送邮件到1749072012@qq.com
  © 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务，数据资源基于CC协议。
  © 本文地址：http://16ao.com/thread-132858.htm
  © Merck Millipore代理MABD10 Anti-DMP1, N-terminus, clone 9B6.3，产品报价联系微信jinshanbio