货号：MABC178

品牌：Merck Millipore

规格：100UL

目录价：￥5666.00

市场价格：￥4816.10

会员价格：￥4532.80

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-P-Rex1 Antibody, clone 6F12 | MABC178 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Molecular Weight: ~186 kDa observed View All» Immunogen: Linear peptide corresponding to human P-Rex 1. View All» Clone: 6F12 View All» Isotype: IgG1κ View All» Background Information: Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1protein (P-Rex1) is a guanine nucleotide exchange factor, which is predominantly expressed in the brain and leucocytes. It exchanges GDP for GTP in Rac 1, resulting in activation of Rac and its downstream signaling molecules that mediate such cellular processes as axon migration and differentiation. View All» Species Reactivity: Human View All» Species Reactivity Note: Demonstrated to react with Human. View All» Application Notes: Western Blot Analysis: A representative lot was used by an independent laboratory to detect P-Rex 1 in PC3 cell lysate (Donald, S.,et al., 2010.), bone-marrow-derived neutrophils from mice (Qin, J., et al., 2009.), and mouse brain sections. (Welch, H, et al., 2005.) View All» Control: THP-1 cell lysate View All» Quality Assurance: Evaluated by Western Blot in THP-1 cell lysate.Western Blot Analysis: A 1:1,000 dilution of this antibody detected P-Rex 1 in 10 µg of THP-1 cell lysate. View All» Purification Method: Protein G purified View All» Presentation: Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: Q8TCU6 View All» Entrez Gene Number: NP_065871 View All» Gene Symbol: PREX1 View All» Alternate Names:

• Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein

• P-Rex1

• PtdIns(3,4,5)-dependent Rac exchanger 1
  View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» Product Name: Anti-P-Rex1, clone 6F12 View All» Concentration: 0.5 mg/mL View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 µL View All» Format: Purified View All» Host: Mouse View All»
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