货号：MAB5514

品牌：Merck Millipore

规格：100UL

目录价：￥5270.00

市场价格：￥4479.50

会员价格：￥4216.00

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Choline Transporter Antibody, clone 62-2E8 | MAB5514 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Hemicholinium-3-sensitive choline transporter (CHT). View All» Immunogen: Recombinant protein from the C-terminus of human CHT. View All» Clone: 62-2E8 View All» Isotype: IgG1 View All» Species Reactivity:

• Human

• Mouse
  View All» Application Notes: Western blot. The antibody detects a 65 kDa band in mouse brain tissue lysate. The CHT immunoreactivity was most abundant in the striatum. Immunohistochemistry 1:2,000 - 1:8,000 Immunocytochemistry Optimal working dilutions must be determined by end user. View All» Presentation: Ascites fluid. Liquid. Contains no preservative. View All» Storage Conditions: Maintain at -20°C in undiluted aliquots for up to 12 months after date of receipt. Avoid repeated freeze/thaw cycles. View All» UniProt Number: Q9GZV3 View All» Entrez Gene Number: NM_021815.2 View All» Gene Symbol:
  • SLC5A7

  • MGC126299

  • MGC126300

  • CHT1

  • hCHT

  • CHT
    View All» Alternate Names: CHT View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • Immunocytochemistry

    • Immunohistochemistry

    • Western Blotting
      View All» Entrez Gene Summary: Choline is a direct precursor of acetylcholine (ACh), a neurotransmitter of the central and peripheral nervous system that regulates a variety of autonomic, cognitive, and motor functions. SLC5A7 is a Na(+)- and Cl(-)- dependent high-affinity transporter that mediates the uptake of choline for acetylcholine synthesis in cholinergic neurons (Apparsundaram et al., 2000 [PubMed 11027560]).[supplied by OMIM] View All» UniProt Summary: FUNCTION: SwissProt: Q9GZV3 # Imports choline from the extracellular space to the neuron with high affinity. Choline uptake is the rate-limiting step in acetylcholine synthesis. Sodium ion- and chloride ion- dependent.SIZE: 580 amino acids; 63204 Da SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.TISSUE SPECIFICITY: Expressed in putamen, spinal cord and medulla. Specific for cholinergic neurons.PTM: Phosphorylated (By similarity).SIMILARITY: SwissProt: Q9GZV3 ## Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. MISCELLANEOUS: Specifically inhibited by nanomolar concentrations of hemicholinium 3. View All» Brand Family: Chemicon View All» Product Name: Anti-Choline Transporter Antibody, clone 62-2E8 | MAB5514 View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 µL View All» Target / Localization: Plasma Membrane View All» Format: Ascites View All» Host: Mouse View All»
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