货号：04-1470

品牌：Merck Millipore

规格：100Ug

目录价：￥4438.00

市场价格：￥3772.30

会员价格：￥3550.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-OX40L (CD252) Antibody, clone RM134L | 04-1470 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Specificity: This antibody recognizes the extracellular domain of OX40L. View All» Molecular Weight: 22 kDa calculated View All» Epitope: Extracellular domain View All» Immunogen: Mouse OX40L cDNA-transfected NRK cells View All» Clone: RM134L View All» Isotype: IgG2bκ View All» Background Information: OX40L (Tumor necrosis factor ligand superfamily member 4; or CD252) is the endogenous ligand of the OX40 receptor. OX40 is localized on activated T-cells and propagates the immune response by promoting division and survival of T-cells, thereby increasing the population of memory CD4 and CD8 T cells produced in response to antigen detection. The OX40/OX40L may also regulate cytokine production and suppress the activity of T-regulatory cells. OX40/OX40L is therefore an important mediator of the immune response. Previous studies have suggested that OX40 signaling maybe involved in the development of autoimmune diseases. View All» Species Reactivity: Mouse View All» Application Notes: Immunohistochemistry Analysis: A representative lot was used by an independent laboratory in mouse lung tissue. (Hoshino, A., et al. (2003). Eur. J. Immunol. 33:861–869.) View All» Control: Mouse OX40L/L5178Y cells View All» Quality Assurance: Evaluated by Flow Cytometry in mouse OX40L/L5178Y cells.Flow Cytometry Analysis: 10 µg of this antibody detected OX40L in mouse OX40L/L5178Y cells. View All» Purification Method: Protein G purified View All» Presentation: Purified rat monoclonal IgG2bκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: P43488 View All» Entrez Gene Number: NP_033478 View All» Gene Symbol:

• Tnfsf4

• Ox40l

• Txgp1l
  View All» Alternate Names:
  • Tumor necrosis factor ligand superfamily member 4

  • OX40 ligand

  • OX40L

  • CD252
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • Flow Cytometry

    • Immunohistochemistry
      View All» UniProt Summary: FUNCTION: Cytokine that binds to TNFRSF4. Co-stimulates T-cell proliferation and cytokine production.SUBUNIT STRUCTURE: Homotrimer. SUBCELLULAR LOCATION: Membrane; Single-pass type II membrane protein. SEQUENCE SIMILARITIES: Belongs to the tumor necrosis factor family. View All» Product Name: Anti-OX40L (CD252), clone RM134L View All» Concentration: 1.0 mg/mL View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Purified View All» Host: Rat View All»
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