货号：01-309

品牌：Merck Millipore

规格：

目录价：￥4601.00

市场价格：￥3910.85

会员价格：￥3680.80

金山科研平台，产品价格货期咨询微信：jinshanbio Description: PDGF-AA, human View All» Trade Name: Upstate (Millipore) View All» Qty/Pk: 10 µg View All» Key Applications: Cell Culture View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Entrez Gene Summary: The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer or as a heterodimer with the platelet-derived growth factor beta polypeptide, where the dimers are connected by disulfide bonds. Studies using knockout mice have shown cellular defects in oligodendrocytes, alveolar smooth muscle cells, and Leydig cells in the testis; knockout mice die either as embryos or shortly after birth. Two splice variants have been identified for this gene. View All» UniProt Summary: FUNCTION: SwissProt: P04085 # Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. Binding of this growth factor to its affinity receptor elicits a variety of cellular responses. It is released by platelets upon wounding and plays an important role in stimulating adjacent cells to grow and thereby heals the wound.SIZE: 211 amino acids; 24043 Da SUBUNIT: Antiparallel disulfide-linked dimer of non-identical (A and B) chains. Homodimers of A and B chains are implicated in transformation processes. Interacts with CSPG4.SUBCELLULAR LOCATION: Secreted.DOMAIN: SwissProt: P04085 The long form contains a basic insert which acts as a cell retention signal.SIMILARITY: Belongs to the PDGF/VEGF growth factor family.MISCELLANEOUS: A-A and B-B, as well as A-B, dimers can bind to the PDGF receptor. View All» Species: Human View All» Brand Family: Upstate View All» Source: Recombinant human protein produced in E. coli. View All» Presentation: Lyophilized with no additives. View All» Storage Conditions: Reconstitution: Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.Storage and Stability: : Lyophilized protein is good until expiration date on label if stored at -20°C to -80°C. Rehydrated protein can be stored for 12 months at -20°C to -80°C. Avoid repeated freezing and thawing. View All» Gene Symbol:

• PDGFA

• PDGF-1

• PDGF-A

• PDGF1
  View All» Product Name: PDGF-AA, human View All» Quality Assurance: Routinely evaluated in an assay using 3T3/NIH fibroblasts View All» Physical Form: Lyophilized View All» UniProt Number: P04085 View All» Entrez Gene Number:
  • NM_002607.4

  • NM_033023.3
    View All» Purification Method: Sterilized through a 0.2 micron membrane filter View All»
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