货号：MAB3150

品牌：Merck Millipore

规格：

目录价：￥2960.00

市场价格：￥2516.00

会员价格：￥2368.00

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Cardiac Troponin I Antibody, a.a. 41-49, clone 284 (19C7) | MAB3150 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: MAB3150 reacts equally with free cardiac troponin 1 (cTn1) and cTn1 forming complexes with other troponin components. It recognizes epitopes that are not perturbed or sterically shielded by other troponin components. There is no cross-reaction with skeletal muscle troponin 1. MAB3150 is not affected by heparin, phosphorylation or oxidation. View All» Epitope: a.a. 41-49 View All» Immunogen: Human native troponin complex. View All» Clone: 284 (19C7) View All» Isotype: IgG2b View All» Species Reactivity:

• Bovine

• Canine

• Goat

• Human

• Mouse

• Pig

• Rat

• Rabbit

• Fish

• Feline
  View All» Application Notes: MAB3150 has been used successfully in ELISA and immunoaffinity purification. Suitable for use with MAB3152 in sandwich ELISA Western blotting: identifies two bands 14kDa and 18kDa which appear to be breakdown products of full length cTn1 (Morjana N., 1998). Optimal working dilutions must be determined by end user. View All» Presentation: Liquid in PBS (pH 7.4) with 0.1% sodium azide. View All» Storage Conditions: Maintain refrigerated at 2-8°C in undiluted aliquots for up to 6 months. View All» UniProt Number: P19429 View All» Entrez Gene Number: NM_000363.4 View All» Gene Symbol:
  • TNNI3

  • TNNC1

  • CMH7

  • MGC116817

  • cTnI
    View All» Alternate Names: cTn1 View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • ELISA

    • Western Blotting
      View All» Entrez Gene Summary: Troponin I (TnI) is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle; see also TNNI1 (MIM 191042). The others are troponin T (TnT; see MIM 191041) and troponin C (TnC; see MIM 191040).[supplied by OMIM] View All» UniProt Summary: FUNCTION: SwissProt: P19429 # Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.SIZE: 210 amino acids; 24008 Da SUBUNIT: Binds to actin and tropomyosin. Interacts with TRIM63.DISEASE: SwissProt: P19429 # Defects in TNNI3 are the cause of familial hypertrophic cardiomyopathy type 7 (CMH7) [MIM:191044]; also designated FHC or HCM. Familial hypertrophic cardiomyopathy [MIM:192600] is a heart disorder characterized by ventricular hypertrophy, which is usually asymmetric and often involves the interventricular septum. The prevalence of the disease in the general population is 0.2%. FHC is clinically heterogeneous, with inter- and intrafamilial variations ranging from benign to malignant forms with a high risk of cardiac failure and sudden cardiac death. & Defects in TNNI3 are the cause of familial restrictive cardiomyopathy (RCM) [MIM:115210]. RCM is an heart muscle disorder characterized by impaired filling of the ventricles with reduced volume in the presence of normal or near normal wall thickness and systolic function. The disease may be associated with systemic disease but is most often idiopathic.SIMILARITY: SwissProt: P19429 ## Belongs to the troponin I family. View All» Brand Family: Chemicon View All» Product Name: Anti-Cardiac Troponin I Antibody, a.a. 41-49, clone 284 (19C7) | MAB3150 View All» Concentration: 1 mg/mL View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 µg View All» Format: Purified View All» Host: Mouse View All»
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