货号：MAB2247-I

品牌：Merck Millipore

规格：100Ug

目录价：￥5513.00

市场价格：￥4686.05

会员价格：￥4410.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Integrin β1 Antibody, clone 12G10 | MAB2247-I View All» Replaces: MAB2247 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Molecular Weight: ~192 kDa observed View All» Immunogen: Purified human β1 Integrin preparation from HT1080 fibrosarcoma cell extract View All» Clone: 12G10 View All» Isotype: IgG1κ View All» Background Information: Integrin beta 1, also known as CD29, is a 130 kDa transmembrane glycoprotein that forms noncovalent complexes with various Integrin alpha subunits (including alpha 1, alpha 2, alpha 3, alpha 4, alpha 5, and alpha 6, also known as CD49a, CD49b, CD49c, CD49d, CD49e, and CD49f, respectively) to form the functional receptors that bind to specific extracellular matrix proteins. Integrin receptors are involved in the regulation of a variety of important biological functions, including embryonic development, wound repair, hemostasis, and prevention of programmed cell death. They are also implicated in abnormal pathological states such as tumor directed angiogenesis, tumor cell growth, and metastasis. Interactions between integrins and the extracellular matrix lead to activation of signal transduction pathways and regulation of gene expression. View All» Species Reactivity: Human View All» Species Reactivity Note: Demonstrated to react with Human. View All» Application Notes: Western Blot Analysis: 0.5 µg/mL from a representative lot detected Integrin β1 in 10 µg of Integrin purified protein.Immunofluorescence Analysis: A representative lot was used in an independent laboratory in mouse lung tissue. (Chen P., et al. (2009). PLoS ONE. 4(8):e6565.) View All» Control: HeLa cells View All» Quality Assurance: Evaluated by Flow Cytometry in HeLa cells.Flow Cytometry Analysis: 1 µg of this antibody detected Integrin β1 in HeLa cells. View All» Purification Method: Protein G purified View All» Presentation: Purified mouse monoclonal IgG1κ in PBS containing 0.1% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: P05556 View All» Entrez Gene Number: NP_002283 View All» Gene Symbol:

• ITGB1

• FNRB

• MDF2

• MSK12
  View All» Alternate Names:
  • Integrin beta-1

  • Fibronectin receptor subunit beta

  • VLA-4 subunit beta

  • CD29
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • Western Blotting

    • Flow Cytometry

    • Immunofluorescence
      View All» Product Name: Anti-Integrin β1, clone 12G10 View All» Concentration: 0.5 mg/mL View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Purified View All» Host: Mouse View All»
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